Difference
The word "best" is an adjective, and adjectives do not take articles by themselves. Because the noun car is modified by the superlative adjective best, and because this makes the noun car definite in this context, we use the. It is best not to do something. Here, we have the adjective best, but this adjective is attached to no noun. No matter who you are, being gay in New York City is easy. From exploring storybook-like neighborhoods to dancing until sunrise at intense circuit parties, there are limitless ways for gay travelers to explore New York. Adverbs
Both sentences could mean the same thing, however I like you best. I like chocolate best, better than anything else can be used when what one is choosing from is not specified I like you the best. Between chocolate, vanilla, and strawberry, I like vanilla the best can be used when choosing from some choices. Thanks for subscribing! Look out for your first newsletter in your inbox soon! Grammar
In the following sentence, however, best is an adjective: "What was best?" If we insert the word the, we get a noun phrase, the best. You could certainly declare that after comparing a number of things, you found that a particular one of those things was the best. That is to say, it was better than any of the others. Great-value hotels in New York City. Reviews, discounts, book online. "Which one is the best" vs. "which one the best is"
So, " It is the best ever " means it's the best of all time, up to the present. " It was the best ever " means either it was the best up to that point in time, and a better one may have happened since then, or it includes up to the present. Home to what is arguably the world's most famous gay bar, The Stonewall Inn, New York is a world leader when it comes to gay nightlife. There is something for everyone in the city that never sleeps. 
Valediction
1 Your example already shows how to use "best" as an adverb. It is also a superlative, like "greatest", or "highest", so just as you would use it as an adjective to show that something is the ultimate example of it's kind when used as an adverb you do so to indicate that the adjective it precedes is to the highest degree possible. The Big Apple has an unrivalled gay scene, as you may well know. Check out our selection of the best gay bars in Fire Island.
Expressions
"Which one is the best" is obviously a question format, so it makes sense that " which one the best is " should be the correct form. This is very good instinct, and you could even argue that the grammar is good, but at best it's unnatural. . 
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5 In Europe, it is not uncommon to receive emails with the valediction With best/kind regards, instead of the more typical and shorter Best/Kind regards. When I see a colleague of mine writing such a phrase, I usually point out that it is a kind of old-fashioned affected valediction which, probably, nowadays, a native English speaker wouldn't. .
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It's best that he bought it yesterday. or It's good that he bought it yesterday. 2a has a quite different meaning, implying that what is being approved of is not that the purchase be made, but that he is the one to make it. 3 "It's best (if) he (not) buy it tomorrow." is not a subjunctive form, and some options do not work well. .